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        {
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  ],
  "verification": {
    "Monte_Carlo_replicates_per_condition": 200000,
    "all_exact_vs_MC_within_five_standard_errors": true,
    "worst_shifted_zero_effect_tail_probability_exact": 0.025,
    "worst_shifted_zero_effect_tail_probability_MC": 0.024385,
    "null_MC_five_standard_error_bound": 0.0017455300054711176
  },
  "plan": {
    "physical_measurements": 0,
    "classification": "PRERECORDED_PLANNING_SIMULATION_NOT_EXPERIMENTAL_DATA",
    "seed": 449113,
    "replicates_per_condition": 200000,
    "thermal_pairs": 12,
    "paired_log_ratio_sd_percent": [
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      0.5,
      0.75,
      1.0,
      1.25,
      1.5,
      1.75,
      2.0,
      2.25,
      2.5,
      2.75,
      3.0
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    "flow_bound_relative": 0.0075,
    "pressure_bound_relative": 0.001,
    "pressure_bound_absolute_Pa": 0.03,
    "maximum_pair_head_difference_Pa": 0.05,
    "head_Pa": 60.2059158,
    "protocol_SHA256": "de71dac17cef7eba3d65928bda57154019d688bcbcb84786339860102e76b4db",
    "analysis_SHA256": "d2e1597590474cabad041bf0bd24ec03d534817ded14af5dfd9d3fb7b6e3b696",
    "assumptions": [
      "Independent normally distributed paired log ratios at the stated between-block SD.",
      "All physical quality gates are assumed to pass; this simulation does not model rejected runs or operator/instrument authenticity.",
      "The conservative planned flow/head bounds are subtracted exactly as in the frozen paired decision.",
      "Alternative effects come from the independent 1D input sensitivity study, not hardware measurements or a confidence interval.",
      "The frozen twelve-pair count and experimental endpoint are not changed."
    ]
  },
  "plan_SHA256": "7a234bf7de55ba5334599cc2f5fe6fe728ece690e5765c4ebf9218fecd9108b4",
  "reference_input_SHA256": "fa353908cab9aa266915167a707fcd26368f603a74cdc471f368e857e5ed3d2c",
  "script_SHA256": "05fc7de7104bc5e25d866f94011075f9cafe8d724dd0d07c635bed48e23ce4f7",
  "limits": [
    "Power is conditional on the stated normal independent paired-log-ratio model, genuine calibration bounds and passing all physical quality gates.",
    "This does not predict the actual physical effect or actual laboratory variation.",
    "Input sensitivity cases are not effect confidence intervals.",
    "No sensor data or completed physical trial is created."
  ]
}